
This time Sam gets player status, and Max is relegated to cameo (although, unlike Sam in Poker Night 1, Max speaks in this game, a lot)
Game:
Poker Night 2

Moxxi from Borderlands, and Reginald Van Winslow returns (and using his proper name this time, rather than just "The Host")
Game:
Poker Night 2

Doug from The Walking Dead (still based on former Telltale IT guy and former Mojo staffer Doug Tabacco)
Game:
Poker Night 2